Nootropic herbs are extracted from seed bearing plants used for cognitive enhancing purposes. It fundamentally makes the brain processing more robust and efficient without the depressed state, mental crash, or unsustainable long term use. Since Nootropic herbs are natural, it is safe to use and the ingredients can be traced back to the source of the plant, unlike synthetic Nootropics. Some common Nootropic herbs extract include Artichoke (Leaf), Bacopa Monniera, Forskolin, Ginkgo Biloba, Huperzine A, and Lion’ s Mane.

Artichoke (Leaf)

The Nootropic herbs, the artichoke is the leaf of the Cynara Scolymus plant. The leaves are rich in luteolin flavonoids and caffeoylquinic acids are known to possess great amounts of antioxidant, lipid lowering properties, and hepatoprotective. In terms of Nootropics, the luteolin flavonoids from the artichoke extract show potent anti-inflammatory response by inhibiting NFkB signaling in the brain cells. This reduction of inflammation in the brain protects the brain from toxins, minimizes the effects of brain aging, and contributes to the stimulation of new neuron cells. The new neuron cells improve memory, increase neuroprotection, cognition, wakefulness and neuroplasticity.

Bacopa Monniera

The Nootropic herbs, Bacopa Monniera is from the Brahmi plant and has been used as a cognitive enhancer for thousand years. Reports show that the Bacopa Monniera prevents the rate of depletion of blood acetylcholine level in the aged human population. The acetylcholine plays a crucial role in the brain and body because it is a neurotransmitter that sends signals to other cells. Studies also show the Nootropic herbs reduces and relieves depression, insomnia, anxiety, and negative effects of stress. Other benefits include improving memory, focus, and hand-eye coordination. It works by balancing serotonin, GABA, and dopamine while reducing the stress hormone cortisol. However, it will take at least two to three months to experience the maximum benefits of Bacopa Monnieri. Therefore, it will not enhance the cognitive abilities instantly but rather it will gradually.


The Nootropic herbs, Forskolin is from the root of the Coleus Forkohlii plant. Clinical studies support the fact that Forskolin treats hypertension, eczema, insomnia, congestive heart failure, and respiratory disorder. Specifically, Forskolin increases the cyclic adenosine monophosphate (cAMP) and cAMP-mediated functions through the activation of the enzyme adenylate cyclase. The increase in cAMP restrain cell degranulation, lowers blood pressure, intraocular pressure, and stimulates lipolysis in fat cells. Additionally, due to the interference with platelet activation factor (PAF), Forskolin restrains the binding of PAF, independently of the cAMP formation. The promotion of vasodilatation (initiates dilation of blood vessels, which decreases blood pressure) increases the blood circulation to the brain, which allows important nutrient and oxygen to flow to the brain. Therefore, the greater the supply of nutrient, oxygen, and glucose, the greater amount of energy with the brain generate. Forskolin also appears to have an effect on membranes that transport proteins and inhibits glucose transport in platelets and other cells.

Ginkgo Biloba

The Nootropic herbs, Ginkgo Biloba is from the leaves of the Maidenhair tree and has been used in the therapeutic application for centuries. Some symptoms Ginkgo Biloba help alleviate are Alzheimer’s disease, vascular dementia, and age-related amnesic conditions. These Nootropic herbs has been shown to have neuroprotective effects on brain neurons against oxidative stress induced by peroxidation.Ginkgo Biloba’s neuroprotective and cognitive enhancing effects have been attributed to its platelet-activating factor (PAF) antagonistic effects and its free radical scavenger activity. Studies have shown Ginkgo Biloba increases the speed of information processing, working memory and executive processing in healthy young subjects. In older subjects with age-related memory impairment, however, have shown positive effects while taking Ginkgo Biloba.

Huperzine A

The Nootropic herbs, Huperzine A is a substance purified from the Chinese club moss called Huperzia Serrata. It is used to treat Alzheimer’s disease and is a very potent inhibitor of the enzyme acetylcholinesterase (AChE). Huperzine A also increases the levels of acetylcholine in the brain by blocking the action of cholinesterase. Acetylcholine plays a crucial role in the formation of new memories. High acetylcholine improves the magnitude of neurotransmitter to the cortex. Additionally, it suppresses the release of glutamate, which suppresses feedback excitation of the cortex. The overall effect is to make the cortical circuits able to respond quickly to sensory relevant input while decreasing excitatory feedback that can hinder memory retrieval. It is reported that Huperzine A has neuroprotective properties against glutamate-induced cell death. This protects neurons from damage due to glutamate, peroxides, and beta-amyloids.

Lion’ s Mane   

The Nootropic herbs, Lion’s Mane is from the mushroom called Hericium Erinaceus. It is linked to nerve growth factor. Nerve growth factor is a neurotrophin which is a small secreted protein that is crucial for the survival, maintenance, proliferation and growth of neurons. It is one of the essential building blocks of neuroplasticity and brain health. The nerve growth factor advocates the growth of axons, nerve cells extension where impulses are conducted. Therefore, the more axons that exist, the better the overall function of the brain. In this case, Lion’s Mane increases nerve growth factor which enhances cognition by promoting myelination, the growth of the lipid and protein sheath that covers and protects the axons. The myelin increases the speed at which impulses travel along the axon by increasing the resistance of the neural cell walls and preventing the impulses from dispersing or leaving the axon. Additionally, myelination lays the foundation for the repair and regrowth of damaged axon. This is vital for protecting the brain from aging or diseases such as Alzheimer’s. Overall, Nootropic herbs enhances cognition which includes improved memory and recalls, and aid with maintaining focus and attention.

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