Acetyl-L-Carnitine (ALCAR) is an amino acid that is essential for muscle movement, brain and heart function, and other body processes. It is considered a Natural Nootropic due to its ability to cross the blood-brain barrier to get from the bloodstream into the brain. In terms of cognitive enhancement, ALCAR produces acetylcholine, which is an essential neurotransmitter required for memory function and learning. Other benefits include improved processing speed, focus, memory, mood, alertness, clarity, and has a fast acting antidepressant properties.
Artichoke Extract is the leaf of the Cynara Scolymus plant. It is one of the most effective and safest PD4E inhibitors. PD4E is an enzyme that breaks down cyclic adenosine monophosphate (cAMP) molecules and blocks the breakdown of cAMP which increases the levels of cAMP in the brain. This can result in an overall increase in cognition, improved memory, and alertness. The leaves are also rich in luteolin flavonoids and caffeoylquinic acids are known to possess great amounts of antioxidant, lipid lowering properties, and hepatoprotective. In terms of Nootropics, the luteolin flavonoids from the artichoke extract show potent anti-inflammatory response by inhibiting NFkB signaling in the brain cells. This reduction of inflammation in the brain protects the brain from toxins, minimizes the effects of brain aging, and contributes to the stimulation of new neuron cells. The new neuron cells improve memory, increase neuroprotection, cognition, wakefulness and neuroplasticity.
Coleus Forskolin is from the root of the Coleus Forkohlii plant. It increases the cAMP and cAMP-mediated functions through the activation of the enzyme adenylate cyclase. The cAMP is the messenger system that relay signals in the brain, increase in cAMP, improve cognitive function, restrain cell degranulation, lowers blood pressure, intraocular pressure, and stimulates lipolysis in fat cells. Additionally, due to the interference with platelet activation factor (PAF), Forskolin restrains the binding of PAF, independently of the cAMP formation.